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颞叶癫痫发作间期SPECT比较及其预后的相关因素分析 被引量:1

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摘要 目的研究不同年龄组颞叶癫痫患者病史、单光子发射计算机断层成像术(SPECT)、长程视频脑电图(VEEG)、头颅影像学资料及与其预后的关系。方法回顾分析我院确诊的111例颞叶癫痫患者病史、发作间期SPECT资料、发作间期VEEG资料、头颅MRI资料及药物疗效,依据年龄分为儿童组(〈12岁)33例,青少年组(12~18岁)35例,成人组(〉18岁)43例,比较三组间异同。结果三组颞叶癫痫患者异常SPECT灌注(P〈0.05)统计学意义,比较难治性与非难治性颞叶癫痫患者的相关因素发现:反复异常脑电图(P〈0.05)、SPECT多灶异常灌注(P〈0.05)、MRI异常(P〈0.05)、对多种药物耐药(P〈0.05)患者预后较差。结论颞叶癫痫患者SPECT显像儿童以异常高灌注为主,青少年及成人以异常低灌注为主;起病年龄小、病程长、发作间期多灶异常灌注、VEEG反复异常、头颅MRI异常及长期不规律服用抗癫痫药物致耐药为颞叶癫痫预后不良的因素。
出处 《中国医药指南》 2013年第18期631-633,共3页 Guide of China Medicine
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