骶骨肿瘤术后伤口感染的相关因素分析

Analysis of related risk factors of wound infection after sacral tumor resection

背景:多数骶骨肿瘤的主要治疗方法是手术,术后伤口感染的发生率较高。目的:分析骶骨肿瘤术后伤口感染的相关因素。方法:回顾1997年9月至2010年8月行骶骨肿瘤切除术462例中术后伤口感染的预防及诊治经验。应用单变量logistic回归分析伤口感染的相关危险因素,对筛选出的因素进行多因素logistic回归分析。结果:462例中57例(12.3%)出现伤口感染,其中52例伤口细菌培养阳性,52例中17例为混合细菌。糖尿病史、手术区曾接受放疗、术中术后直肠破裂、手术历时较长、术后脑脊液漏均是发生伤口感染的独立危险因素。结论:在制定骶骨肿瘤切除计划以及治疗骶骨伤口感染的过程中需考虑危险因素及常见致病菌类型。

Background：Sacrectomy is the main therapeutic modality for sacral tumors;while the incidence of wound infection is high.Objective：To analyze the potential risk factors of postoperative wound infection associated with sacral tumor resection.Methods：Reviewing the prevention,diagnosis and treatment experience of postoperative wound infection in 462 patients who received sacral tumor resection during September 1997 to August 2010,analyzing the related risk factors with univariate logistic regression,and screening the potential risk factors for multivariable logistic regression analysis.Results：57 of the 462（12.3%） cases experienced wound infection,of which 52 wounds were Germiculture Positive.And 17 of the 52 cases were with mixed bacteria.History of diabetes,previous radiation in the operation area,intraoperative or postoperative rectum rupture,long duration of surgery,and postoperative cerebrospinal fluid leakage are all independent risk factors of wound infection.Conclusions：In the process of planning the sacral tumor resection and the treatment of wound infection,risk factors and common pathogenic bacteria types should be considered.