我院他汀类药物治疗费用分析

Analysis of Treatment Costs of the Statins in Our Hospital

目的：评价不同他汀类药物降低低密度脂蛋白胆固醇（LDL-C）相同水平时的费用。方法：对该院6种他汀类药物（普伐他汀10-40 mg/d;辛伐他汀10-80 mg/d;氟伐他汀40-80 mg/d;阿托伐他汀10-80 mg/d;瑞舒伐他汀5-20 mg/d;匹伐他汀1-4 mg/d）进行最小成本比较。结果：降低LDL-C水平〈35%时,辛伐他汀的费用最低;而降低LDL-C水平〉35%时,瑞舒伐他汀的费用最低。合理选择他汀类药物最多可为每位患者每年节约5 617.35元。同种药物原研药与仿制药之间费用差异不大（普伐他汀除外）。结论：应根据具体情况选择药物,既可以实现降脂目标,又可以节约医疗成本,实现资源的最大利用。

OBJECTIVE：To evaluate the treatment cost of different kinds of statins in the same reduction of LDL-C.METHODS：The minimum costs of 6 kinds of statins were compared in our hospital,i.e.pravastatin 10-40 mg/d,simvastatin 10-80 mg/d,fluvastatin 40-80 mg/d,atorvastatin 10-80 mg/d,rosuvastatin 5-20 mg/d,pitavastatin 1-4 mg/d.RESULTS：When the percentage of LDL-C was lowered by 35%,simvastatin was the cheapest treatment choice;while rosuvastatin became preferred when the percentage of LDL-C was lowered by35%.A maximum of 5617.35 yuan per patient per year could be saved when the preferred statin was used.The treatment costs of original drug and generic drugs were similar（except for pravastatin）.CONCLUSIONS：The drugs should be selected according to the situation,so that a lot of medical cost and resources could be saved without reduction of efficacy.