摘要
目的观察眼底血管病变与脑白质疏松的相关性,分析颈动脉内膜中层厚度与脑白质疏松及严重程度的相关性。方法收集我院神经内科病房住院患者或体检者138例,根据磁共振影像,分为脑白质疏松组66例和对照组72例,对所有病人行眼底数码照相分析,应用Scheie法对眼底动脉病变分级,超声测量颈动脉内膜中层厚度,根据Fazekas量表对脑白质疏松程度进行分级,分析对比不同级别的脑白质疏松患者的眼底动脉硬化改变程度、颈动脉内膜中层厚度数值。结果脑白质疏松组与对照组比较,眼底改变程度、颈动脉内膜中层厚度值比较差异有统计学意义(P<0.05)。不同级别脑白质疏松改变,存在眼底动脉硬化程度不同。脑白质疏松轻度改变与中度改变颈动脉内膜中层厚度值比较差异有统计学意义(P<0.05);重度改变与轻、中度改变颈动脉内膜中层厚度值比较差异有统计学意义(P<0.05)。结论眼底改变在一定程度上能够反映脑白质疏松的存在及严重程度,脑白质疏松与颈动脉内膜中层厚度有相关性。
Objective To research of the correlation between retinal arterial sclerosis degree, carotid artery intimae-media thickness and leukoaraiosis. Methods Totally 138 patients and experimenters were divided into LA group （n=66） and normal control group （n= 72） according to brain MRI. All patients were performed eye digital camera analysis, and graded retinal ar-terial sclerosis with Scheie method. Two groups were performed carotid ultrasound inspection, and the IMT of carotid artery was measured. Leukoaraiosis was graded by Fazekas method. Results The differences of retinal arterial changes between LA and the normal control group were statistically significant. The differences of the IMT of carotid artery between the two groups had statistically significant difference. Conclusion Leukoaraiosis has correlation with retinal arterial changes and atherosclero-sis.
出处
《中国实用神经疾病杂志》
2013年第4期1-4,共4页
Chinese Journal of Practical Nervous Diseases
