慢性病病灶特征对脑卒中后认知功能损害的影响

A control study of the chronic disease and focus feature in cognitive impairment of cerebrovascular disease

目的分析不同慢性病史及病变特征对脑卒中后认知障碍的影响程度。方法以回顾性描述方法,采集研究对象的慢性病史及病灶特征信息;应用神经心理学方法,以韦氏成人智能量表(中文版)为工具,评定研究对象的言语功能(VIQ)、操作功能(PIQ)及综合功能(FIQ)。结果存在慢性病史者及皮层受累者VIQ、PIQ、FIQ显著性偏低,左侧病灶者VIQ显著性偏低,右侧病灶者PIQ显著性偏低。结论存在慢性病史者认知损害更为严重,不同部位病变的认知损害有其自身特点。

Objective To observe the intelligence of cerebrovascular disease patients,and explore the relationship between the chronic disease,the focus feature and the cognitive impairment.Methods Totally 167 patients were investigated by case history and focus location.The intelligence was measured by WAIS-RC.Results The VIQ,PIQ and FIQ were reduced significantly in the patients with chronic disease,or the patients of cerebral cortex involved.The VIQ reduced significantly in the patients of left brain focus,moreover the PIQ reduced in right brain.Conclusion The cognitive impairment is severer in patients with chronic disease.The differences of cognitive feature are appeared in different focus locations.