摘要
目的探讨疏血通注射液所致不良反应的一般规律和特点,促进临床合理用药。方法采用回顾性的研究方法,对1979年1月-2013年4月中国知网期刊全文数据库和中国生物医学文献数据库中报道的国内应用疏血通注射液所致的不良反应病例进行统计、分析。结果疏血通注射液引起不良反应在60岁以上的高龄组发生率较高,占53.01%(44/83);不良反应累及多个系统,主要涉及皮肤及附件,占96.38%(80/83),临床表现复杂多样,主要表现为过敏反应,严重者可出现过敏性休克。结论临床医务工作者应了解疏血通注射剂所致不良反应的一般规律和特点,加强其应用的监测,以减少不良反应的发生。
Objective To investigate general rules and characteristics of adverse reactions induced by shuxuetong injection to provide some referential guidance for rational administration in clinic. Methods A retrospective analysis was conducted on 83 reports of ADR induced by traditional Chinese medicine injections during the period from 1978 to 2013 retrieved from CNKI and CBM database. Results ADR of shuxuetong injection often occurred in the people aged over 60, 53.01% (44/83) of total patients. ADR may involve multiple organs and systems, with the dominant damage of skin and female accessories (80/83). Clinical manifestations of ADR were various, and mainly were allergic reactions. Conclusion Doctors and pharmacists should know the general rules and characteristics of ADR. Administration of shuxuetong injection should be under strict monitoring and examination to reduce the occurrence of serious ADR.
出处
《国际中医中药杂志》
2013年第9期809-811,共3页
International Journal of Traditional Chinese Medicine
关键词
疏血通注射液
不良反应
文献分析
Shuxuetong Injection
Adverse drug reactions
Literature analysis