NICU重症患者医院感染的临床分析

Analysis of hospital infection for patients in NICU

目的:对神经内科重症监护病房(NICU)重症患者医院感染进行临床分析,并分析其危险因素,为其临床防治提供依据。方法:共纳入120例入住医院NICU重症患者,完善相关信息的收集,分析其发生感染的情况,并将其分为感染组与非感染组,应用多因素回归分析进行多因素分析。结果:120例NICU重症患者中有20例患者发生医院感染,感染的发生率为16.7%;感染组患者患糖尿病、长期卧床、侵入性操作、白蛋白水平分别为70.0%、75.0%、70.0%、(29.2±3.1)g/L,均明显高于非感染组的45.0%、50.O%、40.0%、(36.8±4.1)g/L,2组差异有统计学意义(P<0.05);对相关因素进一步行多因素分析,结果表明糖尿病史、长期卧床及白蛋白水平低下是NICU重症患者医院感染的独立危险因素(P<0.05)。结论:NICU重症患者发生医院感染与糖尿病史、长期卧床及白蛋白水平低下存在密切的相关性,是其发生的独立危险因素,对于该类患者要积极的给予相应的干预措施,可降低其发生医院感染的风险。

Objective： To analyze the the risk factors of patients in neurology intensive care unit （NICU） ,and provide the basis tor its clinical prevention and treatment. Methods： Included 120 patients in NICU ,divided into infection and the without infection group according to whether the infection occurs. Than multi -factor analysis based on multiple factors regression analysis. Results： About 20 patients in NICU occurred the infection in 120 cases, the infection rate wss 16.7%. The number of diabetes,long - term lie in bed, invasive operation was 70.0% ,75.0% ,70.0% in patients with infection,and the albumin levels （29.2 ＋ 3.1 ） g/L,which were significantly higher than the patients＇ without infection,50.0% ,40.0% ,45.0% and （36.8 ＋ 4.1 ） g/L,there was difference between the two groups （ P 〈 0.05）. After further multi - factor analysis,the results showed that the history of diabetes,long - term lie in bed and low albumin levels were the independent risk factors in patients with infection（ P 〈 0.05）. Conclusion： There were close correlation between patients with infection and diabetes history, and the low level of albumin in long - term. If we could give corresponding intervention measures that could reduce the occurrence of hospital infection.