术尔泰联合玻璃酸钠预防腹盆腔手术后粘连的效果观察

Effect Observation of Shuertai Combined with Sodium Hyaluronate in Prevention of Adhesion after Abdominal and Pelvic Cavity Operation

目的观察术尔泰联合玻璃酸钠预防腹盆腔手术后粘连的效果。方法将腹盆腔手术148例随机分为试验组和对照组各74例。两组术后均行常规生理盐水和术尔泰溶液冲洗,手术结束关腹前试验组于手术创面涂抹玻璃酸钠凝胶,对照组未涂抹玻璃酸钠凝胶。比较两组术后24 h肛门通气排便、体温及腹盆腔粘连情况。结果试验组术后24 h内肛门通气排便率明显高于对照组(χ2=5.78,P=0.02),术后体温≥37.7℃发生率明显低于对照组(χ2=5.19,P=0.02),腹盆腔粘连程度明显轻于对照组(Z=3.27,P=0.001)。结论腹盆腔手术后应用术尔泰联合玻璃酸钠能预防和减少手术后粘连。

Objective To observe the therapeutic efficacy of shuertai combined with sodium hyaluronate in prevention of adhesion after abdominal and pelvic cavity operation.Methods A total of 148 patients after abdominal and pelvic cavity operation were randomly divided into experimental group（n = 74） and control group（n = 74）.After douching with normal saline（NS） and Shuertai solution,sodium hyaluronate was smeared on the wound surface before abdominal suture in experimental group.Control group was not applied with sodium hyaluronate.Anal venting and defecation,body temperature,and abdominal and pelvic cavity adhesion 24 h after operation were compared.Results The incidence rate of anal venting and defecation postoperative 24 hours in experimental group was significantly higher than that in control group（χ2 = 5.78,P = 0.02）;the incidence rate of body temperature ≥37.7℃ in experimental group was significantly lower than that in control group（χ2 = 5.19,P = 0.02）;the degree of abdominal and pelvic cavity adhesion in experimental group was lower than that in control group（Z = 3.27,P = 0.001）.Conclusion Shuertai combined with sodium hyaluronate after abdominal and pelvic cavity operation may prevent and reduce incidence rate of postoperative adhesion.