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液基薄层细胞学在宫颈病变筛查中的应用 被引量:2

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摘要 目的探讨液基薄层细胞学技术(LCT)在宫颈病变诊断中的临床应用价值。方法对宫颈脱落细胞采用LCT检查和Bethesda分级系统(TBS)分类,对低级别鳞状上皮内病变(LSIL)及以上患者行阴道镜下组织病理学活检确诊。结果 2 523例LCT检查结果中,无上皮内病变及恶性病变(NILM)为阴性,阴性率82.44%(2080/2523);以非典型鳞状上皮细胞意义不明确(ASCUS)及以上病变为阳性,阳性率17.56%(443/2523),阳性病变中ASCUS 141例占31.83%;非典型鳞状上皮细胞不除外高级别鳞状上皮内病变(ASCH)37例占8.35%;LSIL 172例占38.83%;高级别鳞状上皮内病变(HSIL)65例占14.67%;鳞状细胞癌(SCC)2例占0.45%,非典型腺细胞(AGC)26例占5.87%。年轻妇女的LCT阳性率最低,与其它年龄组比较差异有统计学意义(P<0.001)。LSIL及以上病变与组织病理学活检的符合率为71.55%。结论采用LCT检查和TBS分类诊断系统能及早发现宫颈病变,提高宫颈癌的检出率。
出处 《右江民族医学院学报》 2013年第4期516-517,共2页 Journal of Youjiang Medical University for Nationalities
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