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化妆品皮肤毒性的动物实验替代方法研究进展 被引量：3

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摘要 随着全球范围的动物福利、动物保护运动发展和实验动物减少、优化、替代（3R）原则的兴起，动物实验的替代成为新兴研究和发展方向。欧盟化妆品规程第7次修正案（2003／15／EC）明确规定逐步禁止化妆品成品动物试验，2009年起禁止化妆品原料进行动物试验，2013年后将禁止用动物试验检测的化妆品原料及成品进入欧盟市场，并列入WTO双边协议的条款。
作者 张洁宏 赵鹏
机构地区 广西壮族自治区疾病预防控制中心
出处 《右江民族医学院学报》 2013年第4期542-544,共3页 Journal of Youjiang Medical University for Nationalities
基金 广西科技基础条件平台建设项目(12-97-18)
关键词 化妆品 毒性试验 替代动物试验
分类号 TQ652 [化学工程—精细化工]
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参考文献23

  • 1EU,Directive 2003/15/EC of the European Parliament——and of the Council of 27February 2003amending CouncilDirective 76/768/EEC on the approximation of the lawsof the Member States relating to cosmetic products[S].Off J Eur Union L66,2003:26-35.
  • 2Annette Mehling,Tove Eriksson,Tobias Eltze,et al.Non-animal test methods for predicting skin sensitization po-tentials[J].Arch Toxicol,2012,86(8):1273-1295.
  • 3Standard Operating Procedure.In vitro skin irritation test:human skin model:epiDermTM-200[S].Version5.0.BfR,2004.
  • 4Macfarlane M,Jones P,Goebel C,et al.A tiered approachto the use of alternatives to animal testing for the safetyassessment of cosmetics:Skin irritation[J].RegulatoryToxicology and Pharmacology,2009,54(2):188-196.
  • 5Mun CG,Aardema MJ,Hu T,et al.Further develop-ment of the EpiDermTM3Dreconstructed human skin mi-cronucleus(RSMN)assay[J].Mutation Research,2009,673(2):92-99.
  • 6Hayes DW Jr,Webb GE,Mandracchia VJ,et al.Full-thickness burn of the foot:successful treatment with Ap-ligraf.A case report[J].Clin Podiatr Med Surg,2001,18(1):179-188.
  • 7张广静,卓金士,金岩,卢涛.人的原代上皮角质形成细胞和永生化的上皮角质形成细胞HaCaT的增殖能力的比较[J].现代生物医学进展,2011,11(1):68-70. 被引量：4
  • 8Petersen AB,Wulf HC,Gniadecki R,et al.Dihydroxyac-etone,the active browning ingredient in sunless tanninglotions,induces DNA damage,cell cycle block and apop-tosis in cultured HaCaT keratinocytes[J].Mutat Res,2004,560(2):173-186.
  • 9Bellei E,Rota C,Bergamini S,et al.Effect of alpha-to-copherol and N-acetylcysteine on benzoyl peroxide toxic-ity in human keratinocytes[J].J Biochem Mol Toxicol,2004,18(2):107-114.
  • 10Spiekstra SW,Dos Santos GG,Scheper RJ,et al.Poten-tial method to determine irritant potency in vitro-com-parison of two reconstructed epidermal culture modelswith different barrier competency[J].Toxicology Invitro,2009,23(2):349-355.

二级参考文献18

  • 1Balls MJ. Future improvements: replacement in vitro methods [J]. TL, 2002. 43 : S159-S731.
  • 2Anon. Statement on the scientific validity of the 3T3 NRU PT test (an in vitro test for phototoxicity) , 9th meeting of ECVAM Scientific Advisory Committee [ C ]. 1-2 October, 1997.
  • 3Spielmann H, Lovell WW, Johnson BE. The Second ECVAM Workshop on Phototoxicity Testing. The report and recommendation of ECVAM workshop 2 [ J ]. ATLA, 2000, 28 : 777-814.
  • 4Medina J,Elsaesser C, Picarles V, et al. Assessment of the phototoxic potential of compo unds and finished topical products using a human reconstructed epidermis [ J ]. IVMT ,2001,14 : 157-168.
  • 5Pape WJ, Maurer T, Pfannenbecker U. The red blood cell phototoxicity test ( photohaemolysis and haemoglobin oxidation ) : EU/COLIPA validation programmeon phototoxicity (Phase Ⅱ ) [ J ]. ATLA, 2000, 29: 245- 289.
  • 6In Vitro 3T3 NRU phototoxicity test. OECD guideline for testing of chemicals.
  • 7Spielmann H, Balls M, Dupuis J, et al. The international EU/COLIPA in vitro phototoxicity validation study: results of Phase Ⅰ/( blind trial ) ; part 1: the 3T3 NRU phototoxicity test[ J]. TIV, 1998, 12 : 305-327.
  • 8YuanLiu, FumihikoSuwa, XinwenWang, et al. Reconstruction of a tissue-engineered skin containing melanocytes[J]. Cell Biology Intemational, 2007, 31:985-990.
  • 9Karin Kehe, Michael Abend, Kai Kehe, et al. Tissue engineering with HaCaT cells and a fibroblast cell line [J]. Arch Dermatol Res, 1999, 291:600-605.
  • 10S.W.Spiekstra a, G.G.dosSantos a et al. Potential method to determine irritant potency in vitro - Comparison of two reconstructed epidermal culture models with different barrier competency [J]. Toxicology in Vitro,2009,23:349-355.

共引文献17

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二级引证文献12

右江民族医学院学报
2013年 第4期

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