摘要
以邻苯二胺与醛为原料,采用盐酸作催化剂,空气为氧化剂,乙醇作溶剂,合成苯并咪唑衍生物,发现芳醛上带有吸电子基时则能够较好地得到目标产物,而芳醛上带有供电子取代基时,反应产物大多为双Schiff碱副产物。其中5个化合物为新化合物,产物结构经1H NMR确证。
With air as the oxidant, 2-phenylbenzimidazole compounds were synthesized from aromatic lalde- hydes and o-phenylenediamine in ethanol catalyzed by hydrochloric acid. It was found that the products were mostly bis-Schiff bases when the arylaldehydes possessed electron-donating groups. The expected products could only be obtained when the arylaldehydes possessed electron-withdrawing groups. From all the compounds five of them were first renorted, and their structures were determined by 1H NMR.
出处
《化学世界》
CAS
CSCD
北大核心
2013年第8期497-499,共3页
Chemical World
关键词
苯并咪唑衍生物
芳醛
吸电子基
邻苯二胺
合成
benzimidazole derivatives
aromatic aldehydes~ electron-withdrawing groups
o-phenylenedia-mine, synthesis