血液灌流串联血液透析救治急性百草枯中毒的临床研究

Clinical study of hemoperfusion and hemodialysis on paraquat poisoning

目的研究血液灌流串联血液透析治疗急性百草枯中毒的临床效果。方法临床按照不同中毒剂量区别治疗,分别分为治疗组:常规治疗+HP串联HD;对照组:单纯常规治疗。结果不同中毒剂量的治疗组与对照组死亡率不同,死亡患者中的存活时间治疗组较对照组长(P<0.05)。结论急性百草枯中毒服毒量越大死亡率越高(P<0.05),服毒量≤100ml中毒患者HP串联HD治疗可明显降低死亡率(P<0.05),临床可以使用血液灌流串联血液透析治疗百草枯中毒的患者,提高患者存活率。

Objective To study different results of comprehensive treatment on acute paraquat - poisoned patients who took different doses. Methods The paraquat - poisoned patients of every stage were divided into two groups ： the inves- tigating groups accepted conventional treatments ＋ HP seriesHD;the control groups accepted simple conventional treat- ments. Results The mortalities were different of patients who took different doses. The death of investigating groups lived longer than the control groups. Conclusion Acute poisoning of paraquat poisoning a greater amount of the higher mortality （ P 〈 0. 05 ） , HP score ~〈 100ml poisoning patients series HD treatment can significantly reduce mortality （ P 〈 0.05 ） , clinical use of hemodialysis and hemoperfusion in the treatment of paraquat poisoning patients, improve the survival rate of the patients.