慢性阻塞性肺疾病患者BODE指数与疲乏症状的相关性分析

Correlation analysis between the BODE index with fatigue symptoms on COPD patients

目的探索稳定期COPD患者BODE指数与疲乏症状的相关性，为临床评估、预测、控制疲乏症状，制定有效的管理方案提供新途径。方法对2011年12月至2013年1月120例稳定期COPD患者进行调查。采用英国医学研究委员会呼吸困难量表（mMRC）、6min步行距离（6MWD）、体重指数（BMI）、肺功能及疲乏量表-14（FS-14）等方法，分析BODE指数与疲乏症状的相关性。结果患者疲乏症状与BODE指数、mMRC成高度线性正相关；与6MWD成高度线性负相关；与FEV。％预计值、BMI成显著性负相关。结论稳定期COPD患者疲乏发病率高，BODE指数及各因子与疲乏症状相关度高，是预测和评估COPD患者疲乏症状的一项客观指标。

Objective To explore the correlation between BODE index with fatigue symptoms on COPD patients, and provide new ways for clinical evaluation, prediction, symptom control and establishment of effective management mode. Methods 120 COPD patients of stable stage were selected to be investigated and analyzed by the Fatigue Scale-14（FS-14）, six-minute walking distance（6MWD）, pulmonary func-tion test and the body mass index （BMI）. Dyspnea was measured using the Medical Research Council （MRC） dyspnea scale. Results The fatigue symptoms showed high positive linear correlation with BODE index and mMRC, and significant negative correlation with 6 MWD, FEVj% and BMI. Conclusions The study shows that fatigue symptoms had a higher prevalence in COPD patients of stable stage. There were a high correlation between fatigue symptoms with the BODE index, mMRC, 6blWD, FEVI% and BMI. The BODE index was a good predictor and evaluation of fatigue symptoms.