补肾化瘀中药外敷联合帕米膦酸二钠改善骨转移癌痛

Clinical Observation on Reliving Pain in Bone Metastasis Patients by Pamidronate Disodium Combined with Bushen Huayu Chinese Medicine

目的:探讨中药外用联合帕米膦酸二钠治疗骨转移性癌痛的临床疗效。方法:将中国中医科学院望京医院收治的骨转移癌痛患者60例随机分为治疗组(30例)和对照组(30例)。两组患者均给予帕米膦酸二钠注射液治疗,治疗组在此基础上加用补肾化瘀中药外敷治疗,比较两组中医证候有效率及止痛效果。结果:中医证候改善情况,治疗组总有效率80%,对照组为40%,差异具有统计学意义(P<0.01)。两组止痛效果比较,治疗组缓解率为83.3%(25/30),高于对照组的46.70%(14/30),差异有统计学意义(P<0.05)。结论:中药外敷联合帕米膦酸二钠治疗骨转移癌痛效果明显优于单用帕米膦酸二钠,可提高患者生存质量。

Objective：To explore the clinical efficacy of Chinese medicine combined with pamidronate disodium on cancer pain in the bone metastatic in patients.Method：Sixty patients were randomly divided into two groups,treatment group with 30 cases and control group with 30 cases.The control group was given pamidronate disodium,the treatment group was given Chinese medicine and pamidronate disodium.Result：The total effective rate in the treatment group was 80%,and was 40% in the control group.The difference was statistically significant（P ＆lt;0.01）.For the analgesic effect,in the treatment group relief rate was 83.3%,which was higher than that in the control group（46.70%）,the difference was statistically significant（P ＆lt; 0.05）.Conclusion：The Chinese medicine combined with pamidronate disodium in treatment of metastatic bone cancer is better than single pamidronate disodium,which can improve the patients’ quality of life in clinical application.