急性百草枯中毒的综合治疗

A comprehensive therapy on acute paraquat poisoning

百草枯是农业常用除草剂,近年来百草枯中毒病人明显增多,且以口服中毒为主,中毒后尚无特效的解毒剂,病死率极高,靶器官主要是肺脏,多脏器功能衰竭和肺纤维化是死亡的主要原因。目前以综合治疗为主,探寻百草枯中毒的有效治疗药物已成为研究热点,本文对临床救治中常用的及近年来新发现的治疗措施作一综述。

Paraquat is a common herbicides extensively used m agriculture, ttecent years, paraquat polsomng get obvlously increased, especially the oral poisoning. There is no specific antidote for the poisoning yet, it has extremely high mortality. The main target organ of paraquat is lung, while the multiple organ failure and pulmonary fibrosis are the leading reasons of death. A comprehensive, symptomatic treatment has been the main therapy strategy, and exploring effective antidote has also become a research hotspot. This article will provide a brief overview on all the traditional methods and new trials about treatment of paraquat poisoning.