椎体成形术对骨转移癌痛患者生活质量的影响

Effect of Vertebroplasty on Quality of Life in Patients with Vertebral Metastases

目的探讨椎体成形术对晚期骨转移癌患者生活质量的影响。方法收集2011年1月~2012年12月,采用椎体成形术治疗脊柱椎体骨转移癌的患者12例,术前、术后1周、术后1个月采用健康调查简表（SF-36）、视觉模拟评分（VAS）对患者生活质量、疼痛改善状况等进行对比分析。结果生理职能（RP）、情感职能（RE）无变化;生理功能（PF）、活力（VT）、社会功能（SF）、精神健康（MH）呈上升趋势;躯体疼痛（BP）在术后1周与术前相比呈上升趋势,术后1个月与术后1周相比呈轻微下降趋势;总体健康（GH）在术前、术后1周和术后1个月相比呈下降趋势。术后1周和术后1个月相对于术前VAS评分显著下降（P〈0.001）。术后1周相对于术前疼痛改善率为61.46%,术后1个月相对于术前疼痛改善率为57.96%。结论椎体成形术可以短期内有效改善椎体转移癌患者的生活质量,减轻疼痛。

Objective To explore the effect of vertebroplasty on quality of life in patients with vertebral metastases. Methoas 12 cases of vertebral metastases were collected from Jannuary, 2011 to November, 2012, all the cases were treated with vertebroplasty, MOS health survey 36-item Short Form and Visual Analogue Scale （VAS） were used to evaluate the quality of life and pain symptom before and l week and I month after operation. Results There was no difference in the score of role physical （RP） and role emotional （RE）. And there was an upward trend in the score of physical function （PF）, vitality （VT）, social function （SF） and mental health （MH）. The score of bodily pain （BP） increased 1 week after operation, and decreased 1 month after operation. The score of general health （GH） decreased after 1 week and l month. The score of VAS were significantly lower 1 week and 1 month after operation than before operation （P〈0.001）. And the pain im- provement rate was 61.46% and 59.76% respectively. Conclusion The vertebroplasty can improve the quality of life and alleviated the pain symptom in patients with vertebral metastases in a short period.