摘要
目的:探讨氢氧化钙治疗慢性根尖周炎的临床疗效及机制。方法:回顾性分析于2011年6月至2011年10月间就诊我科的慢性根尖周炎患者,随机选取采用氢氧化钙封闭剂或碘仿糊剂治疗的符合标准的患者各50例,收集资料分析治疗效果。结果:氢氧化钙封闭剂和碘仿糊剂治疗组患者年龄及性别的组间差异不显著(P>0.05);两方法治疗后不同疼痛级别患者的的差异具有统计学意义(P<0.05),氢氧化钙封闭剂疼痛级别低于碘仿糊剂治疗组;治疗后随访至6个月至1年,氢氧化钙封闭剂的成功率高于碘仿糊剂治疗组(P<0.05);实时定量PCR检测治疗前后细菌量变化,两方法治疗后根尖周细菌数量均显著减少,氢氧化钙封闭剂治疗组细菌量降低显著高于碘仿糊剂治疗组(P<0.05)。结论:氢氧化钙治疗慢性根尖周炎效果优于碘仿糊剂治疗,可能是由于更有效的抑制了根管内细菌的数量。
Objective： To explore the clinical effects and mechanisms of calcium hydroxide in treating patients with chronic periapical periodontitis.Method： We retrospectively analyzed patients with chronic periapical periodontitis,who received treatment of calcium hydroxide and iodoform paste respectively.The effects were analysed.Result： There is no significant differences between patients of two groups（P0.05）;the grade of pain were different（P0.05）;the cure rates showed significant differences between two groups（P0.05）;bacterial counts decreased after treatment,patients received calcium hydroxide showed a more significant decrease.Conclusion： Patients with chronic periodontitis treated with calcium hydroxide appeared to have a better effect,probably due to the decrease of numbers of bacteria.
出处
《河北医学》
CAS
2013年第10期1457-1459,共3页
Hebei Medicine
基金
广东省佛山市医学类科技攻关项目
编号:2012037
关键词
慢性根尖周炎
根管治疗
氢氧化钙
碘仿糊剂
细菌数
Chronic periapical periodontitis
Root canal therapy
Calcium hydroxide
Lodoform paste
Bacterial count
