期刊文献+

基于胆固醇的新型小分子胶凝剂的合成与胶凝行为 被引量:8

Synthesis and Gelation Properties of Cholesterol-Based New Low-Molecular-Mass Gelators
下载PDF
导出
摘要 设计合成了3种以丙二胺为连接臂(L)、苯环为A单元的A(LS)2型双胆固醇(S)类小分子胶凝剂: 化合物1(邻位), 化合物2(间位)和化合物3(对位), 考察了其在30种溶剂中的胶凝行为. 结果表明, 苯环取代位置的不同对化合物的胶凝性质有决定性影响. 就胶凝溶剂的数量来讲, 对位取代的化合物3的胶凝能力明显高于邻位和间位取代的化合物1和2. 此外, 化合物2和3可以形成5个室温胶凝体系, 且化合物3/二甲苯凝胶透明、柔韧,以至于可以形成超分子薄膜. 傅里叶变换红外(FTIR)光谱和核磁共振氢谱(1H NMR)研究表明, 胶凝剂分子之间的氢键和π-π堆积作用在凝胶形成过程中发挥了一定的作用. X射线衍射(XRD)研究表明在化合物1/苯凝胶中, 胶凝剂分子聚集为六方堆积结构, 进而形成贯穿整个凝胶体系的网络结构. Three novel dimeric cholesteryl-based low-molecular-mass gelators (LMMGs), which have the structure A(LS)2, were designed and synthesized. In the structures, 1,3-diaminopropane is a linker (L), A is a benzene ring, and S is cholesteryl. According to the positions of the substituents on the benzene ring, the as-prepared compounds are denoted by 1 (o-position), 2 (m-position), and 3 (p-position), respectively. Their gelation properties were evaluated in 30 solvents. It was revealed that the relative positions of the two cholesteryl moieties on the benzene ring play a crucial role in the gelation behaviors of the compounds. In terms of the number of solvents gelled by the tested compounds, compound 3 is a more versatile gelator than compounds 1 and 2; compounds 2 and 3 can form five gels at room temperature. Furthermore, the compound 3/xylene gel is transparent and flexible, and forms a supramolecular film in the wet state. Fourier- transform infrared (FTIR) spectroscopy and IH nuclear magnetic resonance (IH NMR) spectroscopy studies demonstrated that intermolecular hydrogen bonding and TT- TT stacking among the molecules of the gelators play important roles in the gelation process. X-ray diffraction (XRD) analysis showed that the aggregate of compound 1 from its benzene gel adopts a hexagonal packing mode as the elementary structure of the gel networks.
出处 《物理化学学报》 SCIE CAS CSCD 北大核心 2013年第9期2005-2012,共8页 Acta Physico-Chimica Sinica
基金 国家自然科学基金(21273141)资助项目~~
关键词 小分子胶凝剂 胆固醇 自组装 室温胶凝 凝胶薄膜 Low-molecular-massgelator Cholesterol Self-assembly Room temperature gelation Gel film
  • 相关文献

参考文献2

二级参考文献46

  • 1Friggeri,A.;Gronwald,O.;Bommel,K.J.C.;Shinkai,S.;Reinhoudt,D.N.J.Am.Chem.Soc.,2002,124:10754
  • 2Li,Y.G.;Liu,K.Q.;Liu,J.Langmuir,2006,22:7016
  • 3Abdallah,D.J.;Weiss,R.G.Adv.Mater.,2000,12:1237
  • 4Bommel,K.J.C.;Friggeri,A.;Shinkai,S.Angew.Chem.Int.Ed.,2003,42:980
  • 5Jung,J.H.;John,G.;Masuda,M.;Yoshida,K.;Shinkai,S.;Shimizu,T.Langmuir,2001,17:7229
  • 6Amaike,M.;Kobayashi,H.;Shinkai,S.Bull.Chem.Soc.Jpn.,2000,73:2553
  • 7Winnik,F.M.Chem.Rev.,1993,93:587
  • 8Ringsdoff,H.;Venzmer,J.;Winnik,F.M.Macromolecules,1991,24:1678
  • 9Birks,J.B.Rep.Prog.Phys.,1975,38:903
  • 10Sagawa,T.;Fukugawa,S.;Yamada,T.;Ihara,H.Langmuir,2002,18:7223

共引文献11

同被引文献247

引证文献8

二级引证文献25

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部