氟哌噻吨美利曲辛改善慢性胃炎症状的效果

THE EFFECT OF DEANXIT ON IMPROVING SYMTOMPS OF CHRONIC GASTRITIS

目的探讨氟哌噻吨美利曲辛(黛力新)改善慢性胃炎症状的效果。方法选择2011年12月—2012年6月于我院门诊就诊的60例伴有轻中度抑郁焦虑的慢性胃炎病人,按就诊顺序分为对照组和治疗组,分别给予常规消化内科治疗和常规消化内科治疗+黛力新治疗,疗程4周。入组前、治疗2周及4周后分别进行消化道症状量表评分和汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评分,比较治疗前后变化。结果治疗2周及4周后,治疗组的消化道症状评分较对照组显著下降(F=24.93、44.65,P<0.05),且精神症状较对照组明显改善(F=9.79～74.92,P<0.05)。结论黛力新能显著改善慢性胃炎病人的临床症状,包括精神和躯体两方面的症状。

Objective To assess the efficacy of Deanxit for improving symptoms of chronic gastritis. Methods Sixty patients with chronic gastritis-accompanying mild to moderate depression and anxiety-visited our clinic, during 2011.12-2012.06, were enrolled in this study. The patients were divided into control group （routine therapy） and treatment group （routine therapy plus Deanxit）. The course of therapy was four weeks. The score of gastrointestinal symptoms, HAMD and HAMA before and two and four weeks after therapy was cor^ducted and compared. Results After two- and four-week therapy, the score of symptoms in the treatment group was lower than that in the control （F=24.93,44.65;P〈0.05） ,and mental symptoms improved （F=9.79- 74.92,P〈0.05）. Conclusion Deanxit can significantly improve patients＇ clinical symptoms, including both psychiatric and so- matic.