摘要
目的 研究细胞凋亡在幕上星形细胞瘤中的意义。方法 用免疫组化方法对56例幕上星形细胞瘤的常规切片进行自然凋亡细胞检测。结果 AI随着星形细胞瘤级别 (恶性度 )的增设而增加 ,存活组和死亡组间AI有显著性差异 ,AI>0.5%组与<0.5 %组间术后一年生存率有显著性差异。结论 AI可以提示幕上星形细胞瘤的预后 ,且AI>0.5 %的患者预后差。AI还可以提示肿瘤的生物学行为 。
Objective To study the effect of cell apoptosis in supratentorial astrocytomas. Methods Apoptotic cells were detected in 56 supratentorial astrocytomas cases with immunohistochemistry. Results Apoptotic index (AI) was increased with malignancy of the astrocytomas grading. Significant difference was observed between the AI of the survuival group (AI>0.5%)and that of the death group (AI<0.5%). Conclusion Ai could serve as an index of the biological behavior of the tumor and a parameter for the grading of the astrocytomas astrocytomas.
出处
《浙江临床医学》
2000年第11期721-722,共2页
Zhejiang Clinical Medical Journal
关键词
幕上星形细胞瘤
凋亡
术后一年生存率
Supratentorial astrocytomas
Apoptosis One-year survival rate