射频消融治疗子宫肌瘤的疗效及其安全性

Safety and efficacy of radiofrequency ablation in the treatment of fibroids

目的探讨超声引导下射频消融治疗子宫肌瘤的疗效及安全性。方法回顾性分析2007-11至2011-10本院门诊行射频消融治疗的196例子宫肌瘤患者的有效率、术中术后阴道流血排液情况、体温情况、腹痛情况、月经情况及需再次手术的严重并发症发生情况。结果本组196例中,总有效率达97.4%,治愈率达57.1%,其中黏膜下肌瘤的总有效率为100%。术中患者有轻到中度腹痛,术后4～6 h疼痛减轻。术后阴道流血2～30 d,1周内干净者占91.9%。患者术后1～3个月月经恢复正常,仅1例术前重度贫血未纠正,术后感染大出血行子宫切除。结论超声引导下射频消融治疗子宫肌瘤,是一种能够保留子宫的安全有效简单的治疗手段。

Objective To study the safety and efficacy of radiofrequency ablation （RFA） in the treatment of fibroids. Meth- ods One hundred and minety - six fibroids patients who had undergone RFA treatment in outpatient department were selected from November 2007 to Octcber 201 I. The effective rate, vaginal bleeding during and after operation, temperature, abdominal pain, mensis and other serious complications which needed operation once again were retrospectively analyzed. Results In all the 196 cases, the total effective rate was 97.4%, the curative rate was 57. ! %, the total effective rate of submucous myoma was 100%. The mild to moderate abdominal pain was endured during operation, and the pain disappeared in 4 -6 hours after operation. The vaginal bleeding after operation lasted for 2 -30 days, and in 91.9% of patients lasted within one week. Menses restored to normal in 1 to 3 months. Only 1 patient with severe anemia that was not corrected before operation was finally subjected to hysterectomy because of infection and hemorrhage after operation. Conclusions Ultrasound guided radiofrequency ablation is a safe, effective and simple method of treating fibroids and preserving the uterus.