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急性胰腺炎中的损伤相关分子模式 被引量:3

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摘要 急性胰腺炎(acute pancreatitis,AP)是多种病因引起胰酶激活,以胰腺局部炎症反应为主要特征,伴或不伴有其他器官功能改变的疾病。其初始阶段的局部炎症反应已被证实了是由胰腺腺泡细胞的损伤及坏死介导的。细胞损伤后释放的物质被称为损伤相关分子模式(Damageassociated molecular pattern,DAMPs)。近年来越来越多的证据证明坏死的胰腺腺泡细胞释放的DAMPs介导的炎症反应是决定胰腺损伤及疾病严重程度的关键因素。本文就急性胰腺炎中的DAMPs作一综述。
出处 《中华胰腺病杂志》 CAS 2013年第4期280-283,共4页 Chinese Journal of Pancreatology
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