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新型毒品急性中毒心肌损害及猝死的原因探讨 被引量:3

Myocardial damage and sudden death caused by acute poisoning of new drug
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摘要 目的:探讨新型毒品(苯丙胺类)急性中毒的临床症状、体征、实验室检查、治疗及导致猝死的原因。方法:对我科收治的20例苯丙胺类急性中毒患者的临床资料进行回顾性分析;并对我市20例因吸食苯丙胺类新型毒品猝死者尸检报告进行综合分析。结果:急性中毒患者均有心率增快及心电图异常,75%有血压升高。尸检发现猝死者心肌细胞均有明显改变。结论:苯丙胺类可导致心肌细胞严重损害,引起急性心力衰竭,甚至猝死。 Objective:To study the clinical symptoms, signs, laboratory examination, treatment, and the cause of sudden death poisoned by the new drug (amphetamine-type). Method:Twenty patients with acute drug poisoning in our hospital and 20 cases of sudden death because of new drugs were retrospectively analyzed. Result: All the patients with acute poisoning had increased heart rate and electrocardiographic abnormality, 75% had increased blood pressure. Autopsy showed that there were obvious changes in myocardial cells. Conclusion: Amphetaminetype drugs can lead to serious damage of myocardial cells, acute heart failure, even sudden death.
出处 《临床心血管病杂志》 CAS CSCD 北大核心 2013年第8期611-613,共3页 Journal of Clinical Cardiology
基金 湖北省自然科学基金(No:2011CDB096)
关键词 苯丙胺类 中毒 心肌细胞 猝死 amphetamine poisoning myocardial cell sudden death
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