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微囊藻毒素-LR的离体鳃灌流研究 被引量：2

RESEARCH ON ISOLATED GILL PERFUSION WITH MICROCYSTIN-LR
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摘要 随着水体富营养化进程的加剧,有毒蓝藻的频繁暴发已成为一个世界性的难题。自1878年Francis报道了世界上首例由于接触有毒蓝藻而引发的牲畜中毒事件以来,已经有许多关于鱼类、爬行动物、鸟类和哺乳动物接触蓝藻而中毒甚至死亡的案例。
作者 张伟 谢平
机构地区 中国科学院水生生物研究所
出处 《水生生物学报》 CAS CSCD 北大核心 2013年第4期772-775,共4页 Acta Hydrobiologica Sinica
基金 国家自然科学基金(31070457)资助
关键词 微囊藻毒素 摄取 排泄 鳃灌流 Microcystin Intake Excrection Gill perfusion
分类号 X172 [环境科学与工程—环境科学]
  • 相关文献

参考文献26

  • 1Francis G. Poisonous Australia lake [J]. Nature, 1878, 18: 11-12.
  • 2Carbis C R, Simons J A, Mitchell G F, et al. A biochemical profile for predicting the chronic exposure of sheep to Mi- croscystisaeruginosa, an hepatotoxic species of blue-green alga [J]. Research in Veterinary Science, 1994, 57(3): 310- 316.
  • 3Chen J, Zhang D W, Xie P, et al. Simultaneous determination of microcystin contaminations in various vertebrates (fish, turtle, duck and water bird) from a large eutrophic Chinese lake, Lake Taihu, with toxic Microcystis blooms [J]. Science of the Total Environment, 2009, 407(10): 3317-3322.
  • 4Mohamed Z A, Carmichael W W, HusseinA A. Estimation of microcystins in the freshwater fish Oreochromisniloticus in an Egyptian fish farm containing a Microcystis bloom [J]. Environmental Toxicology, 2003, 18(2): 137-141.
  • 5张榜军,李效宇.微囊藻细胞抽提物亚慢性暴露导致小鼠肝脏氧化应激(英文)[J].水生生物学报,2009,33(6):1088-1094. 被引量：2
  • 6Dawson R. The toxicology of microcystins [J]. Toxicon, 1998.36(7): 953-962.
  • 7孙瑜,黄朴,徐立红.微囊藻毒素LR影响人肝细胞HL7702的ERK及JNK的蛋白磷酸化[J].水生生物学报,2011,35(1):180-182. 被引量：5
  • 8Nishiwaki-Matsushima R, Ohta T, Nishiwaki S, et al. Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR [J]. Journal of Cancer Research and Clinical Oncology, 1992, 118(6): 420-424.
  • 9Dietrich D, Hoeger S. Guidance values for microcystins in water and cyanobacterial supplement products (blue-green algal supplements): a reasonable or misguided approach [J]? Toxicology and Applied Pharmacology, 2005, 203(3): 273- 289.
  • 10Gaete V, Canelo E, Lagos N, et al. Inhibitory effects of Mi- croeystis aeruginosa toxin on ion pumps of the gill of fresh- water fish [J]. Toxieon, 1994, 32(1): 121-127.

二级参考文献14

  • 1陈加平,翁登坡,傅文宇,徐立红.微囊藻毒素LR对大鼠淋巴细胞DNA的损伤效应[J].水生生物学报,2004,28(6):677-678. 被引量：10
  • 2Pichardo S,Jos A,Zurita J L,et al.The use of the fish cell lines RTG-2 and PLHC-1 to compare the toxic effects produced by microcystins LR and RR[J].Toxicol in Vitro,2005,19(7):865-873.
  • 3Svircev Z,Krstic S,Miladinov-Mikov M,et al.Freshwater cyanobacterial blooms and primary liver cancer epidemiological studies in Serbia[J].Environ Sci Health C Environ Carcinog Ecotoxicol Rev,2009,27(1):36-55.
  • 4M.Krishna,H.Narang.The complexity of mitogen-activated protein kinases(MAPKs) made simple[J].Cellular and Molecular Life Sciences,2008,65(22):3525-3544.
  • 5Junttila M R,Li S P,Westermarck J.Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival[J].The FASEB Journal,2008,22(4):954-965.
  • 6Galabova-Kovacs G,Kolbus A,Matzen D,et al.ERK and beyond:Insights from B-Raf and Raf-1 conditional knockouts[J].Cell Cycle,2006,5(14):1514-1518.
  • 7Kennedy NJ,Davis RJ.Role of JNK in tumor development[J].Cell Cycle,2003,2(3):199-201.
  • 8Iyoda K,Sasaki Y,Horimoto M,et al.Involvement of the p38 mitogen-activated protein kinase cascade in hepatocellular carcinoma[J].Cancer,2003,97(12):3017-3026.
  • 9Komatsu M,Furukawa T,Ikeda R,et al.Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3[J].Toxicology Sciences,2007,97(2):407-416.
  • 10Wei Y,Weng D,Li F,et al.Involvement of JNK regulation in oxidative stress-mediated murine liver injury by microcystin-LR[J].Apotosis,2008,13(8):1031-1042.

共引文献5

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二级引证文献11

水生生物学报
2013年 第4期

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