中文版蒙特利尔认知评估量表在阿尔茨海默病与血管性痴呆中的应用研究

The application of Montreal Cognitive Assessment Chinese version in differentiation of Alzheimer＇s disease and vascular dementia

目的探讨中文版蒙特利尔认知评估量表（MoCA）在阿尔茨海默病（AD）及血管性痴呆（VD）中的应用。方法选取62例AD患者（AD组）和54例VD患者（VD组），采用王炜等翻译的中文版MoCA量表对2组患者的视空间与执行能力、命名、注意力等子项目进行评分。评分后，对2组患者各子项目评分、诊断吻合率及中文版MoCA量表的组间信度进行比较分析。结果2组患者在视空间与执行能力、注意力、延迟回忆及总分等方面比较，差异有统计学意义（P〈0．05）。AD组与VD组患者的诊断吻合率分别为100．00％和98．15％，差异有统计学意义（P〈0．05）。2名评定员对患者所进行的MoCA量表评分呈高度相关性，ICC值：0．911～1．000，95％可信区间波动范围较小。结论中文版MoCA量表可用于AD和VD的诊断，且对AD和VD有一定的鉴别诊断作用，具有良好的应用价值。

Objective To assess the use of the Chinese version of Montreal Cognitive Assessment （MoCA） in differentiating Alzheimer＇s disease （AD） and vascular dementia （VD）. Methods A total of 62 patients with AD and 54 patients with VD were recruited for this study. All subjects were subject to examination using MoCA to collect information in terms of their visuospatial/executive function, attention, language, abstraction delayed recall and orientation. The demographic data of the subjects was also were collected and analyzed. Results It was shown that there were statistically significant differences between the AD and VD patients with regard to their scores of visuospatial / executive, attention, delayed recall （P 〈 0.05）. The rate of diagnostic coincidence was 100% in AD patients using MoCA Chinese version, and 98.15% in VD patients, with a statistically significant difference between the two groups. There was high correlation in all items of MoCA between the two evaluators （1CC： 0. 911 - 1. 000）. Conclusion Montreal Cognitive Assessment Chinese version can be used for the diagnosis of AD and VD, and the scale can help differentiate AD and VD.