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生物钟基因NPAS2的研究进展 被引量：9

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摘要 生物钟为生物体内一种内在的生物节律，是地球上的生物为适应自然环境在进化过程中形成的，在分子水平上受到CLOCK、BMALl（brain and muscle ARNT—likeprotein1，、Perl、Per2、Per3、Cry1、
作者 吴超 杨盛力 赵志辉
机构地区 华中科技大学同济医学院
出处 《山东医药》 CAS 2013年第31期91-94,共4页 Shandong Medical Journal
关键词 NPAS2基因 生物钟基因 生物节律 抑癌基因
分类号 Q344 [生物学—遗传学]
  • 相关文献

参考文献28

  • 1Yi C, Mu L, de la Longrais IA, et al. The circadian gene NPAS2 is a novel prognostic biomarker for breast cancer[ J]. Breast Canc- er Res Treat, 2010,120 ( 3 ) :663-669.
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  • 4Brunskill EW, Witte DP, Shreiner AB, et al. Characterization of npas3, a novel basic helix-loop-helix PAS gene expressed in the de- veloping mouse nervous system[ J]. Mech Dev, 1999,88 (2) :237- 241.
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  • 6Reick M, Garcia JA, Dudley C, et al. NPAS2 : An Analog of Clock Operative in the Mammalian Forebrain[ J]. Science, 2001, 293 (5529) :506-509.
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  • 9徐晨,钱睿哲,金惠铭.生物钟基因与心血管疾病[J].中国病理生理杂志,2006,22(7):1450-1453. 被引量：9
  • 10Englund A, Kovanen L, Saarikoski ST, et al. NPAS2 and PER2 are linked to risk factors of the metabolic syndrome[J]. J Circadi- an Rhythms, 2009, (7) :5.

二级参考文献52

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共引文献13

同被引文献45

  • 1吴超,张金玲,杨盛力,赵志辉.孤儿核受体Rev-Erbα功能与表达调控研究进展[J].山东医药,2013,53(30):98-101. 被引量：5
  • 2朱晓彤.抑郁症昼夜节律生物钟的变化[J].中国行为医学科学,2005,14(3):271-272. 被引量：5
  • 3徐晨,钱睿哲,金惠铭.生物钟基因与心血管疾病[J].中国病理生理杂志,2006,22(7):1450-1453. 被引量：9
  • 4Lin YM, Chang JH, Yeh KT, et al. Disturbance of circadian gene expression in hepatocellular carcinoma [ J ]. Mol Carcinog, 2008, 47 (12) :925-933.
  • 5Dai H, Zhang L, Cao M, et al. The role of polymorphisms in cir- cadian pathway genes in breast tumorigenesis [ J ]. Breast Cancer Res Treat, 2011,127(2) :531-540.
  • 6Krugluger W, Brandstaetter A, Krllay E, et al. Regulation of genes of the circadian clock in human colon cancer: reduced peri-od-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors[ J]. Cancer Res, 2007,67 (16) :7917-7922.
  • 7Relles D, Sendecki J, Chipitsyna G, et al. Circadian gene expres- sion and clinicopathologic correlates in pancreatic cancer [ J ]. J Gastrointest Surg, 2013,17(3) :443-450.
  • 8Bhatti P, Cushing-Hangen KL, Wicklund KG, et al. Nightshirt work and risk of ovarian cancer[ J]. Oecup Environ Med, 2013,70 (4) :231-237.
  • 9Parent MI, E1-Zein M, Rousseau MC, et al. Night work and the risk of cancer among men[ J]. Am J Epidemiol, 2012,176 (9) : 751-759.
  • 10Savvidis C, Koutsilieris M. Circadian rhythm disruption in cancer biology[J]. Mol Med, 2012(18) :1249-1260.

引证文献9

二级引证文献39

山东医药
2013年 第31期

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