胃液查抗酸杆菌对肺结核的诊断价值

Investigation of the diagnostic value of pulmonary tuberculosis by checking acid-fast bacilli in gastric juice

目的探讨胃液结核分枝杆菌检查对成人肺结核的诊断价值。方法对34例患者的胃液进行涂片、TBDNA及结核菌培养;痰液进行涂片、TB-DNA及结核菌培养,同时行酶联斑点实验、结核抗体及PPD,并对其阳性率进行比较。结果痰结核菌涂片\培养及TB-DNA检测阳性率明显高于胃液结核菌涂片、培养及TB-DNA阳性率,两者比较差异有统计学意义(P<0.01);T-SPOT.TB、痰TB-DNA、PPD、TB-DOT/TB-CK检测在结核病诊断中显示出高度敏感性。结论成人胃液检查抗酸杆菌作为肺结核诊断价值有限。而痰细菌学检查仍是确诊肺结核的特异方法。

Obiective To investigate the diagnostic value of pulmonary tuberculosis by checking acid-fast bacilli in gastric juice. Methods Gastric juice from 34 patients was examined with smear, TB-DNA and mycobacterial culture. Their sputum was also examined with smear, TB-DNA and mycobacterial culture, as well as enzyme-linked spot experi- ment, tuberculosis antibody and PPD. Their positive rates were compared. Results The positive rate of detection by sputum with smear, mycobacterial culture and TB-DNA was significantly higher than that by gastric juice （P〈0. 01） ; It showed a high sensitivity of T-SPOT. TB, sputum TB-DNA, PPD and TB-DOT/TB-CK in detecting pulmonary tubercu- losis. Conclusion It has limited diagnostic value of pulmonary tuberculosis by checking acid-fast bacilli in gastric juice. For adult patients, bacteriologic examine with sputum is still the specific method to diagnose pulmonary tuberculosis.