基于“治未病”理念下的四维一体综合干预技术防治CRF临床研究

CLINICAL RESEARCH OF QUATERNITY COMPREHENSIVE INTERVENTION TECHNOLOGY IN CONTROLLING CRF BASEDING ON “PREVENTIVE TREATMENT OF DISEASE” IDEA

目的探讨自拟中医药口服方,灌肠方,沐浴方及穴位按摩联合运用的四位一体,全方位,多靶点综合干预技术,观察治疗CRF患者的临床疗效。方法符合纳入CRF标准的患者随机分为治疗组(实施中医药四位一体干预技术组)和对照组(口服西药包醛氧淀粉组);观察二组患者客观症状的改善,肌酐(Scr)、尿素氮(Bun),内生肌酐清除率(Ccr)等生化指标变化,评定疗效。结果经3个疗程90 d的治疗比较,治疗组和对照组CRF患者的Scr,Bun,Ccr变化进行比较有极其显著差异P﹤0.01)。结论四位一体综合干预技术防治CRF疗效显著,值得临床推广应用。

Objective： To investigate the multi-target comprehensive intervention technology with the combined quaternity use of traditional chinese medicine oral administration, enema prescription, bath lotion and point massage and observe the clinical efficacy in patients with CRF. Methods： The patients with CRF were randomly divided into treatment group implemented with the quaternity intervention technology and control group given with western medicine aldehyde oxide starch, and the curative effects were estimated by observing objective symptoms improvement and the change of biochemical index including Scr, Bun and Ccr Of the patients in two groups. Results： The results showed that there were significant differences between two groups in the improvement of Scr, Bun, Ccr （P 〈 0.01） of the patents after 3 courses （90 days） of treatments. Conclusion： R could be concluded that the quatemity intervention technology is significantly effective in prevention and control of CRF, and worthy of clinical application.