左氧氟沙星与莫西沙星治疗老年AECOPD的疗效研究

Comparative study of the efficacy and safety between levofloxacin and moxifloxacin in the treatment of senile patients with acute chronic obstructive pulmonary disease

目的观察临床AECOPD患者中应用莫西沙星的疗效。方法在我院肺病科诊断为AECOPD患者中选取60例患者,随机分为莫西沙星组和左氧氟沙星组各30例,接受不同抗生素的治疗。比较两组的有效率、细菌清除率。结果两组的有效率以及细菌清除率差异没有统计学意义。结论 AECOPD患者在应用莫西沙星注射液能取得与左氧氟沙星注射液相同的有效率和细菌清除率。

Objective To observe the curative effect of moxifloxacin injection in the treatment of senile patients with acute exacer- bation of chronic obstructive pulmonary disease （AECOPD）. Methods 60 patients with AECOPD were randomly and evenly divided into two groups. The group A was treated with moxifloxacin, and the group B was treated with levofloxacin respectively. The effective rate and the eradication rate of bacteria were compared between the two groups. Results There was no statistical difference on the effective rate and bacterium eradication rate between the moxifloxacin group and the levoiloxacin group. Conclusion Moxifloxacin injection has the similar curative effect as levofloxacin injection in the treatment of senile patients with AECOPD. Further high-quality RCTs should be car- ried out to provide more reliable evidence.