嘉兴市地表水中兽用抗生素的污染现状调查

A Study on the Veterinary Antibiotics Contamination in Groundwater of Jiaxing

建立了适合长三角地区重要生猪养殖基地嘉兴市环境水体中4类(四环素类、磺胺类、大环内酯类、喹诺酮类)共10种常用兽用抗生素同时检测的固相萃取与液相色谱质谱(LC-MS/MS)联用技术,对该地区10个典型村镇河道断面和21个市区主要河网监控断面开展调查.结果表明,村镇河道中抗生素污染严重,10种抗生素总浓度为65.6～467.0 ng.L-1.其中,四环素类和磺胺类浓度分别为40.8～253.0 ng.L-1和未检出～165.0 ng.L-1;大环内酯类和喹诺酮类浓度分别为3.1～14.68ng.L-1和未检出～14.54 ng.L-1.市区河网污染相对较轻,10种抗生素总浓度为20.1～61.2 ng.L-1,其中四环素类浓度为未检出～44.0 ng.L-1;磺胺类、大环内酯类和喹诺酮类浓度则分别低于2.7、6.3和21.6 ng.L-1.

Liquid chromatography and tandem mass（LC-MS /MS） followed with solid-phase extraction（SPE） was developed for simultaneously determining four classes（tetracyclines,quinolones,macrolides and sulfonamides） of ten commonly used veterinary antibiotics in groundwater of Jiaxing city,an important pig breeding base in the Yangtze River Delta region.Samples were taken from 10 typical rural river sections and 21 main urban river sections.Results revealed severe pollution existed in the rural river environment.The total concentration of ten antibiotics was as high as 65.6-467.0 ng.L-1,among which tetracyclines and sulfonamides respectively ranged in 40.8-253.0 ng.L-1 and undetected（nd）-165.0 ng.L-1,macrolides and quinolones respectively ranged in 3.1-14.68 ng.L-1 and nd-14.54 ng.L-1.By comparison,the pollution level in urban rivers was much lower.The total concentration of ten antibiotics ranged in 20.1 ng.L-1 to 61.2 ng.L-1,among with tetracyclines varied from undetected to 44.0 ng.L-1,while sulfonamides,macrolides and quinolones were respectively below 2.7 ng·L-1,6.3 ng·L-1 and 21.6 ng·L-1.