武汉市某医院新生儿院内败血症调查

Investigation on Nosocomial Septicemia of Neonates in a Wuhan Hospital

目的:了解新生儿院内败血症的流行病学特征,为制定有效的防治措施提供科学依据。方法:采用回顾性调查方法收集2004年1月-2012年12月武汉市某医院新生儿病房患儿的相关资料,并进行统计分析。结果:新生儿院内败血症发病率明显下降,凝固酶阴性葡萄球菌、肠球菌及真菌感染明显增加,耐苯唑西林的葡萄球菌检出率显著增加,危险因素更多与侵入性操作相关。结论:新生儿院内败血症的发病率、致病菌分布及其耐药性以及危险因素均已发生了变迁,医院应对其进行动态监测,及时掌握其变化趋势,才能更好地有效防治。

Objective：To learn about the epidemiological characteristics of neonatal nosocomial septicemia, and provide scientific basis for effectively preventing and controlling neonatal nosoeomial septicemia. Methods：We collected data in neonates with nosoeomial septicemia in our hospital by a retrospective survey from January 2004 to December 2012, and the data were analyzed statistically. Results：The incidence of neo-natal nosoeomial septicemia decreased significantly during the period, and coagnlase - negative staphylococcus, enteroeoccus and fungal infections increased significantly, methieillin- resistant staphylococcus aureas（MRSA） detection rate increased significantly, and risk factor was invasive procedures. Conclusion：The incidence, pathogen distribution and drug resistance, and risk factors in neonates with nosoeomial septicemia have all changed. Dynamic monitoring should be made to understand their changing trend to effectively prevent and treat the disease.