摘要
目的观察中药治疗单纯疱疹性角膜炎(HSK)的疗效。方法随机将96例(96眼)HSK患者分为2组,对照组单纯采用西药局部给药,治疗组同时加用玉屏风散加味治疗,疗程4周。测量视力,记录症状体征改变,角膜荧光素染色,随访12个月。结果 (1)治疗后2组视力均提高,治疗组视力改善优于对照组,F=14.398,P=0.000。(2)治疗组和对照组的角膜溃疡面修复率分别为(82.69±10.68)%和(71.25±13.15)%,t=8.964,P=0.000。(3)治疗组痊愈、显效、有效和无效率分别是70.83%、20.83%、8.33%和0.00%,对照组分别是47.92%、27.08%、18.75%和6.25%,Z=-2.531,P=0.011。(4)治疗组6个月和12个月首次复发率分别是11.8%和20.6%,对照组分别是21.7%和47.8%,χ2=5.257,P=0.022。结论玉屏风散加味联合西药治疗HSK在改善近期症状体征和预防远期复发方面较单纯应用西药治疗有明显优势。
Objective To observe the efficacy on herpes simplex keratitis(HSK) treated with Chinese medicine.Methods Ninety-six cases(96 eyes) of HSK were randomized into two groups.In a control group,the simple local medication of western medicine was applied.In a treatment group,theModified YupingfengPowder was supplemented at the same time.The duration of treatment was 4 weeks.The vision was checked.The changes in symptoms and physical signs were recorded.The corneal fluorescein staining was conducted.The follow-up visit was done for 12 months.Results(1) The vision was improved after treatment in the two groups,and the improvement in the treatment group was superior to the control group.F = 14.398,P = 0.000.(2) The repair rate of corneal ulcer was(82.69 ± 10.68) % in the treatment group and was(71.25 ± 13.15) % in the control group,t = 8.964,P = 0.000.(3) The curative rate,markedly effective rate,effective rate and failed rate were 70.83%,20.83%,8.33% and 0.00% in the treatment group separately;and those were 47.92%,27.08%,18.75% and 6.25% in the control group separately.Z =-2.531,P = 0.011.(4) The first recurrence rates were 11.8% and 20.6% in 6 and 12 months separately in the treatment group,those were 21.7% and 47.8% separately in the control group.χ2 = 5.257,P = 0.022.Conclusion Modified YupingfengPowder combined with western medicine achieves the advantages at relieving the short-term symptoms and physical signs and preventing from the long-term recurrence as compared with simple western medicine in the treatment of HSK.
出处
《世界中西医结合杂志》
2013年第8期812-814,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
单纯疱疹病毒
角膜炎
玉屏风散
中西医结合
疗效
Herpes Simplex Virus
Keratitis
Yupingfeng Powder
Integration of Chinese and Western Medicine
Efficacy