绝经后OSAS与心血管疾病危险因素的相关性

Correlation between OSAS and the risk factors of angiocardiopathy in postmenopausal women

目的分析探讨女性绝经后患阻塞性睡眠呼吸暂停综合征(OSAS)与心血管疾病危险因素的相关性。方法本研究选取患有OSAS的绝经后女性患者150例作为观察组和未患OSAS的对照组150例,分析不同程度OSAS和心血管危险因素的相关性。结果观察组的BMI指数、颈围、腰围、收缩压、舒张压、HDLC和hs-CRP水平均高于对照组(P<0.05或P<0.01)。不同程度OSAS患者相比较,BMI指数、颈围、腰围、收缩压、hs-CRP总体均数不同,重度OSAS组总体均数均最高(P<0.01)。OSAS的严重程度与BMI、颈围、腰围、臀围、收缩压、HDLC和hs-CRP水平呈正相关关系,与LDLC呈负相关关系(P<0.05或P<0.01)。结论女性绝经后患OSAS可增加患心血管疾病的危险性,并且危险性的增加程度与OSAS的严重程度成正比。

Objective To analyze the correlation between obstructive sleep apnea syndrome （OSAS） and the risk factors of an- giocardiopathy in postmenopausal women. Methods This study chose 150 postmenopausal women with OSAS as an observation group and chose 150 postmenopausal women without OSAS as a control group. For analyzing the correlation between the different severity of OSAS and the risk factors of angiocardiopathy in these cases. Results The level of BMI, neck circumference, waist cir- cumference, systolic blood pressure, diastolic blood pressure, HDLC and hs-CRP in the observation group were higher than the control group （P〈0.05 or P〈0.01）. To compare the different severity of OSAS, there were different population mean of BMI, neck circumference, waist circumference, systolic blood pressure and hs-CRP, and the severe OSAS group had the highest population mean （P〈0.01）. The severity of OSAS had a positive correlation with the level of BMI, neck circumference, waist, hip circumfer- ence, systolic blood pressure, HDLC and hs-CRP, and had a negative correlation with the level of LDLC （P〈0.05 or P〈0.01）. Conclusion There will be a higher risk of angiocardiopathy in postmenopausal women with OSAS. And the risk may be increasing With the severity of OSAS.