ADA检测在胸腔积液中的诊断价值

目的探讨胸腔积液中腺苷脱氨酶(ADA)的检测对胸腔积液性质的判断价值。方法回顾性调查我科2012-01—2013-01诊断明确的胸腔积液患者临床资料,共66例,其中41例结核性胸腔积液,25例恶性胸腔积液,对不同疾病结果ADA水平进行分析。结果 ADA水平在结核性胸腔积液中较恶性胸腔积液有明显增高,但恶性胸腔积液中发现2例血液系统恶性肿瘤,其ADA异常增高。结论胸腔积液ADA增高对结核性胸膜炎有重要的诊断价值,但异常增高的ADA水平要警惕血液系统恶性肿瘤可能。

Objective To explore the diagnostic value of Adenosine deaminase（ADA）detection in pleural effusion.Methods The clini- cal data of 66 patients diagnosed definitely with pleural effusion from the inpatients of respiratory department between January 2012 and Jan- uary 2013 were retrospectively investigated, including 41 patients with tuberculous pleural effusion and 25, patients with malignant pleural ef- fusion.The values of ADA between the two groups were compared.Results There is a more significant rising of ADA value in tuberculosis pleural effusion than in malignant pleural effusion ; however there are abnormally high values of ADA in 2 cases diagnosed with malignant tumor in blood system.Conclusion The rise of ADA in pleural effusion has significant diagnostic value for tuberculous pleurisy.But the ab- normal high value of ADA may hint for the possibility of malignant tumor in blood system.