c-myc蛋白在不同毛色羊驼皮肤中的定位及表达

Localization and Expression of c-myc Protein in Different Colors of Alpaca Skin

为了探索c-myc蛋白在羊驼皮肤中的定位及表达情况,以不同毛色的成年羊驼为研究对象,采用免疫组织化学方法检测c-myc蛋白在羊驼皮肤组织中的表达和定位。结果显示,c-myc在羊驼皮肤毛囊毛球部细胞中呈阳性表达,根据光密度值分析得出c-myc在棕色羊驼毛囊中显著表达,其相对表达量是白色羊驼的5.51倍。研究表明c-myc可能参与羊驼毛色形成。

This experiment was conducted to explore the localization and expression of c-myc in different colors of alpaca skin.The tissues were obtained from white and brown adult alpacas＇ skins.The protein expression and the localization of c-myc were measured by immunohistochemistry.The positive signals of c-myc were found in hair bulb of hair follicle,and the comparative expression level of c-myc in brown alpacas was 5.51 times higher than that in white ones according to the average optical density analysis which indicated that c-myc may involve in the regulation of hair color formation.