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尿毒症患者抗生素脑病17例临床分析 被引量:4

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摘要 尿毒症患者因贫血、营养不良、机体免疫力低下等原因,容易并发各种感染。头孢类抗生素具有抗菌谱广、组织穿透力强等优点,被广泛应用于尿毒症患者感染的治疗。尿毒症患者由于肾小球滤过率下降,影响了抗生素的代谢和清除,如果使用不当,极易出现中枢神经系统症状。现对我院2008年3月至2011年3月17例尿毒症患者抗生素脑病进行回顾性分析,探讨尿毒症患者发生抗生素脑病的药物种类、临床特点、治疗及转归,报告如下。
作者 马云伶
出处 《中国药物与临床》 CAS 2013年第9期1231-1232,共2页 Chinese Remedies & Clinics
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  • 1Brink B, Kimland E, Von Euler M. An unusual case of a side effect. Cefotaxime-induced confusion in a patient with renal failure Lakartidningen, 2003, 100:2370-2371.
  • 2Fishbain JT, Monahan TP, Canonico MM. Cerebral manifestations of cefepime toxicity in a dialysis patient. Neurology, 2000,55:1756-1757.
  • 3Herishanu YO, Zlomik M, Mostoslavsky M ,et al. Cefuroximeinduced encephalopathy. Neurology, 1998, 50:1873-1875.
  • 4Martinez-Rodriguez JE,Barriga FJ, Santamaria J, et al. Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure. AmJ Med , 2001,111:115-119.
  • 5Ferrara N, Abete P, Giordano M, et al. Neurotoxicity induced by Cefepime in a very old hemodialysis patient. Clin Nephrol,2003, 59: 388-390.
  • 6Sugimoto M, Uchida I, Mashimo T, et al. Evidence for the involvement of GABA(A) receptor blockade in convulsions induced by cephalosporins. Neuropharmacology, 2003 ,45:304-314.
  • 7Cohen,D,G.B.Appel,B,Scully, et al. Pharmacokinetics of cefi riaxone in patients with renal failure and in those undergoing hemodialysis.Antimicrob.Agents Chemother,1983,24:529-532.
  • 8Stoeckel K,P.J.McNamara,G.Hoppe-Seyler,et al.Single-dose cefiriaxone kinetics in functionally anephric patients .Clin.pharmaco1.Ther,1983,33:633-641.

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  • 1贺瑞萍,郭永英.抗生素类药物对神经系统的毒性反应[J].中国药事,2004,18(12):774-775. 被引量:32
  • 2张石革.抗真菌药的进展及临床合理应用[J].中国全科医学,2005,8(22):1866-1867. 被引量:10
  • 3彭建华,杨波,潘健涛.尿毒症血液透析患者肺部感染病原菌特点及药敏分析[J].医学临床研究,2007,24(4):647-649. 被引量:6
  • 4王海燕.肾脏病学[M].3版.北京:人民卫生出版社,2008:8262.
  • 5张宪安,主编.实用药源性疾病[M].北京:中国医药科技出版社,1997.304.306.315.
  • 6Moe S M, Sprague S M. Uremic encephalopathy[ J~. Clin Nephrol, 1994,42(4) :251-256.
  • 7Schmidt P, Musshoff F, Hilgers C, et al. Brain amino acid abnormalities in kidney disease and diabetes mellltus [ J]. Forensic Sci Int, 2004,142( 2-3 ) :221-227.
  • 8Sugimoto M, Uchida I, Mashimo T, et al. Evidence for the involvement of GABA (A) receptor blockade in con- vulsions induced by cephalosporins [ J ]. Neuropharmacol-ogy, 2003,45(3) :304-314.
  • 9陈鑫谦,金有豫,汤光.新编药物学[M].12版.北京:人民卫生出版社,2011:53-54.
  • 10吴红艳.尿毒症患者应用头孢菌素诱发脑病10例分析[J].中国保健营养(中旬刊),2014,24(3):1540.

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