摘要
在真核细胞中,自噬(autophagy)是细胞通过降解自身胞质中的部分蛋白和部分细胞器以度过饥饿,并清除氧化损伤的异常大分子及细胞器,从而在应激中维持细胞稳态的过程。自噬的发生是以双层膜囊泡的形成为特征的,因而这种双层膜囊泡被命名为自噬体(autophagosome)。自噬分为大自噬、小自噬和分子伴侣介导的自噬。
出处
《华中科技大学学报(医学版)》
CAS
CSCD
北大核心
2013年第4期501-504,共4页
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
基金
国家自然科学基金资助项目(No.30672480)
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