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关于晚期糖基化终末产物的研究进展 被引量:5

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摘要 1984年Vlassara等人首次提出晚期糖基化终末产物(AGE)这一概念,近年来对于AGE的研究备受关注。研究发现AGE参与了氧化应激、炎症反应等病理变化,同时,AGE还参与了慢性。肾脏病、糖尿病肾病、动脉粥样硬化等疾病的发生及进展过程。本文就AGE的结构、与疾病的关系、药物干预等方面作一综述。
作者 赵方圆
出处 《山东医学高等专科学校学报》 2013年第5期394-396,共3页 Journal of Shandong Medical College
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同被引文献42

  • 1高霞,张红霞,高聆,陈青,姜秀云,管庆波,赵家军.2型糖尿病患者轻度认知功能障碍和血清AGEs水平的关系[J].山东大学学报(医学版),2009,47(9):11-13. 被引量:13
  • 2彭亮,李知敏.灰兜巴抗糖尿病作用的实验研究[J].时珍国医国药,2010,21(12):3060-3061. 被引量:7
  • 3薛金山,林勇.阻塞性睡眠呼吸暂停低通气综合征患者血清糖基化终末产物的变化[J].中华结核和呼吸杂志,2007,30(2):155-156. 被引量:1
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  • 6Tahara N, Yamagishi S, Mttsui T, et al. Serum levels of advanced glyca- tion end products (AGEs) are independent correlates of insulin resistance in nondiabetic subjects [ J ]. Cardiovasc Ther, 2012,30 ( 1 ) :42 - 48.
  • 7Ostendorp T, Leclere E, E alichet A, et al. Structural and functional in-sight into RAGE activation by multimeric S100B[ J]. EMBO J, 2007,26 (16) :3868 - 3878.
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  • 10刘征,王兵.姜德友辨治消渴重症验案举隅[J].上海中医药杂志,2008,42(5):7-8. 被引量:2

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