马来酸单甲酯构型转化反应的研究

Isomerization of Monomethyl Maleate

目的 :探讨硫脲、盐酸和亚硫酸氢钠催化下马来酸单甲酯的构型转化反应。方法 :正交试验和方差分析。结果 :盐酸用量和反应时间对结果的影响具统计学差异 ,而硫脲和亚硫酸氢钠的用量对结果的影响不具备统计学差异。结论 :盐酸用量和反应时间对马来酸单甲酯的构型转化反应均有高度显著性影响 。

Objective To investigate the isomerization of monomethyl maleate catalyzed by the combination of H 2NCSNH 2,HCl and NaHSO 3.Methods Orthogonal experiment and analysis of variance were used.Results The use level of HCl and the reaction time had statistical difference respectively,but the use level of H 2NCSNH 2 and NaHSO 3 hadn't.Conclusion For the isomerization of monomethyl maleate,the use level of HCl and the reaction time has high significance influence respectively,but the use level of H 2NCSNH 2 and NaHSO 3 hasn't.