茵栀黄注射液辅助治疗新生儿母乳性黄疸临床疗效观察

目的:观察茵栀黄注射液辅助治疗新生儿母乳性黄疸的临床疗效,探讨提高治疗新生儿母乳性黄疸疗效的措施。方法:选择2011年3月～2012年10月,在我院治疗的伴母乳性黄疸的新生儿96例,在患儿家长知情同意的情况下,均分为对照组(n=48例)和观察组(n=48例),对照组给予基础治疗,观察组给予基础治疗结合茵栀黄注射液辅助治疗,比较两组患儿治疗前后血清总胆红素(TBiL)水平的动态变化、治疗6d后的临床疗效及治疗过程中的不良反应情况。结果:两组患儿治疗1～6d中每天TBiL水平比较,差异均具有统计学意义(P<0.05);治疗6d后显效与好转例数比较,差异具有统计学意义(P<0.05);有效与无效例数比较,差异无统计学意义(P>0.05);两组患儿的不良反应例数比较,差异无统计学意义(P>0.05),观察组优于对照组。结论:在新生儿母乳性黄疸的基础治疗中,应积极辅助茵栀黄注射液治疗,可促进患儿TBiL水平改善,提高临床疗效,且不增加治疗中的不良反应。

Objective：To observe the clinical effect of Yinzhihuang injection adjuvant therapy for neonatal breast milk jaundice and research research the measures to improve the clinical effect.Method：Collect 96 neonates with neonatal breast milk jaundice,they were divided into the control group （n=48 patients）and the observation group （n=48 patients）,compared with that the dynamic changes of serum bilirubin （TBiL）level before and after treatment,the clinical effect and adverse reactions after 6 days＇ treatment.Result：There was a significant（P0.05）in the number of valid and invalid cases;there was no significant （P〉0.05）in the number of adverse reactions cases,the observation group was better than the control group.Conclusion：During treating the neonatal breast milk jaundice,it should add the Yinzhihuang injection,ti could promote the improvement in children TBiL level,improve the clinical effect and did not increase the adverse reactions in the treatment.