甘草酸二铵注射液治疗急性荨麻疹的疗效观察

Therapeutic Effect of Diammonium Glycyrrhizinate Injection in the Treatment of Acute Urticaria

目的:观察甘草酸二铵注射液治疗急性荨麻疹的疗效和安全性。方法:将68例急性荨麻疹患者随机分为两组,A组给予甘草酸二铵注射液2mg/d,维生素C注射液3.0g/d,静脉滴注两周;B组给予10%葡萄糖酸钙注射液20ml/d,维生素C注射液3.0g/d,静脉滴注两周,口服氯雷他定胶囊10mg/d。结果:A、B两组有效率在14d时差异无统计学意义(P>0.05),分别为97.06%、94.12%,在7d时差异有统计学意义(P<0.05),分别为88.24%、67.65%。结论:甘草酸二铵注射液是治疗急性荨麻疹快速、安全、有效的药物。

Objective： To observe the therapeutic effect and safety of diammonium glycyrrhizinate injection in the treatment of acute urticaria. Methods： Sixty-eight patients were randomly divided into two groups （including A and B）： A were administrated with diammonium glycyrrhizinate injection 200mg/d and vitamin C injection 3.0g/d for two weeks;B were administrated with 10% calcium gluconate injection 20ml/d and vitamin C injection 3.0g/d for two weeks,and also orally with the clarityne capsule 10mg/d. Results：No significance was found between A and B in 14 days （P〉0.05）,while great significance was found between both groups in 7 days （P〈0.05）. Conclusions：The diammonium glycyrrhizinate injection was effective and safety for the treatment of acute urticarial.