分子仿生体系在纳米生物工程应用中的研究进展

Progress of molecular biomimetics systems in nano-bioengineering

分子仿生研究在纳米生物工程领域具有重要的研究意义,近年来相关方面的工作得到了迅速发展.分子仿生的研究主要是在分子水平上对一些典型的生物分子,如磷脂、肽和蛋白等结构与功能模拟,重新设计或组装成与其结构和功能相似的新的仿生体系,研究和探索其在生物体中的自组装过程、识别能力以及物质传输等功能.在分子尺度上认识和理解生物结构单元在生物体中的物理化学机制,为新型仿生体系的构建和生物材料的研发提供重要的实验依据.

Molecular biomimetic system is an emerging hot field in nano-bioengineering. It has been developed rapidly in recent years. The research of molecular biomimetics focuses on the structure and function for typical biomolecules assembly, such as liposome, peptide and protein. These molecules can be assembled into novel biomimetic systems whose functions are similar to themselves. In this field, for these biomolecules, we study their self-assembly process, the ability of bio-recognization and transporting gust molecules. In this process, we try to recognize and understand the physical chemistry mechanism for these units in biosystems. We also try to provide important scientific basis for designing novel biomimetic systems and biomaterials.