手性无机纳米粒子:生物应用的新机遇

Chiral inorganic nanoparticles: New opportunities in bioapplication

近年来,以手性生物分子和无机纳米粒子为基元构建的手性纳米结构因其具有新颖而独特的物理化学性质受到研究人员的广泛关注.手性分子与无机纳米粒子的耦合实现了手性从分子尺度向纳米尺度的跨越,将为光学和生物应用带来新的机遇.本文介绍了生物分子诱导的半导体纳米粒子的手性,系统阐述了手性无机纳米结构的构筑及光学性质,对手性纳米粒子的生物效应进行了简要介绍,并展望了手性纳米结构未来发展的前景和挑战.

In recent years, chiral nanostructures composed of chiral biomolecules and inorganic nanoparticles have attracted many scientists＇ interest because of their unique physical and chemical properties. The coupling between chiral molecules and inorganic nanoparticles opens a door toward development of chirality study from molecular level to nanoscale, and brings new application opportunities not only in optics but also in biology. In this review, biomolecule-induced chirality of semiconductor nanoparticles is introduced, the fabrication and optical properties of chiral inorganic nanostructures are systematically elucidated, and the biological effect of chiral nanoparticles is described. Moreover, future developments and challenges in this field are also discussed.