Flash双源CT冠脉成像联合双能量心肌灌注显像对冠心病的诊断价值

Diagnostic value of dual-source CT angiography plus CT perfusion in coronary artery disease

目的:探讨Flash双源CT(DSCT)冠状动脉成像(DS-CTA)联合双能量心肌灌注显像(DS-CTP)一站式检查对冠心病的诊断价值。方法:对60例临床考虑冠心病的患者行DSCT检查,所有患者均接受冠状动脉造影检查。以冠状动脉造影为标准诊断法,根据冠脉造影结果分为狭窄<50%(阴性)和狭窄≥50%(阳性,诊断冠心病),计算DS-CTA联合DS-CTP(平行试验)诊断冠心病的灵敏度、特异度和准确度。结果:DS-CTA诊断冠心病的灵敏度、特异度和准确度分别为84%、93%和89%;DS-CTA联合DS-CTP(平行试验)诊断冠心病的灵敏度、特异度和准确度分别为94%、91%和92%,与单独DS-CTA比较,灵敏度和准确度稍有提高,而特异度稍有下降,但都没有达到显著水平。结论:DS-CTA联合DS-CTP对冠心病诊断具有很高的诊断价值。但DS-CTA与DS-CTA联合DS-CTP诊断价值无显著差异。

AIM：To evaluate the feasibility of diagnosing coronary stenosis and myocardial ischemia with a single dualenergy CT （DSCT） acquisition method. METHODS： Sixty patients underwent dualsource dual energy CT and conventional coronary angiography （CAG）. CAG results served as the “gold standard” to evaluate the diagnosis of coronary artery disease （CAD） and stenosis ≥50% （positive）. We assessed the sensitivity, specificity and concordance rate of DSCTA plus DSCTP （parallel trial） in diagnosis of CAD. RESULTS： Sensitivity of DSCTA was 84%, specificity was 93%, and concordance rate was 89%. Combination of DSCTA and DSCTP （parallel trial） resulted in a sensitivity of 94%, specificity of 91%, and concordance of 92%. Compared with DSCTA, sensitivity and concordance is slightly improved, whereas there was a slight decrease in specificity but without reaching significance. CONCLUSION： DSCTA plus DSCTP provide a high diagnosis for CAD. DSCTA plus DSCTP with DSCTA shows no significant difference in the diagnostic value.