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右美托咪定在老年患者腰-硬联合麻醉中的应用 被引量:6

Application of Dexmedetomidine in Combined Spinal-Epidural Anesthesia(CSEA) of the Elderly
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摘要 目的:探讨右美托咪定在老年患者腰一硬联合麻醉中的镇静效果,为临床麻醉提供更好的镇静方案。方法:选择手术麻醉的100例患者,按照随机原则平均分为右美托咪定组(包括A、B、C三组)、空白组及丙泊酚组,对比5组患者中麻醉前、后5分钟、30分钟、60分钟时HR(心率)、MAP(平均动脉压)及Ramsay评分。结果:右美托咪定组和丙泊酚组在麻醉后Ramsay评分高于麻醉前;在麻醉30分钟后B、C及丙泊酚组Ramsay评分结果优于空白组。在麻醉后30分钟,C组患者HR水平低于其他组。结论:对老年患者腰硬联合麻醉使用右美托咪定剂量控制在0.2~0.5ug/kg·h能有效保证患者的镇静效果,同时不会产生不良反应。 Objective: To discuss the calming effect of dexmedetomidine in CSEA of the elderly and provided a better calming method for clinical, anesthesia. Method: 100 patients received anesthesia were divided randomly and equally into dexmedetomidine group (including A, B, C group), blank group and propofol group. I-IR, MAP and Ramsay grades before anesthesia, 5 min 30 min 60 min after anesthesia of all groups were compared. Result: Ramsay grades after anesthesia of dexmedetomidine group and propofol group were higher than before anesthesia. Ramsay grades of B, C and propofol group 30 min after anesthesia were higher than blank group. HR level of C group 30 min after anesthesia was lower than other groups. Conclusion : Dose of Dexmedetomidine in application of CSEA of the elderly should be controlled at 0. 2 ~ 0. 5ug/kg h as to ensure the calming effect without adverse reactions.
出处 《中国民族民间医药》 2013年第16期33-34,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词 右美托咪定 腰硬联合麻醉 老年患者 Dexmedetomidine CSEA Elderly patients
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