需经皮冠状动脉介入治疗的不同类型冠心病患者的临床特征分析

Analysis on the Clinical Features of CHD Patients Needing PCI Treatmentof Different Clinical Patterns

目的探讨不同临床类型的冠心病患者的临床特征和危险因素。方法选取2010年11月至2011年3月解放军总医院收治的需经皮冠状动脉介入治疗的冠心病患者118例,比较不同类型患者的临床资料、实验室检查指标和冠状动脉造影结果。结果在选取的118例冠心病患者中,急性心肌梗死(AMI)46例,不稳定型心绞痛(UAP)62例,稳定型心绞痛(SAP)10例。AMI组患者中吸烟者比例高于UAP组和SAP组,入院时收缩压及脉压低于后两组,但AMI组患者患Ⅲ级高血压的比例高于SAP组;同时AMI组患者白细胞(WBC)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、D-二聚体(DD)、C反应蛋白(CRP)等指标高于UAP和SAP组;但三组患者冠状动脉狭窄程度的差异无统计学意义。结论吸烟史、WBC、CK、CK-MB、DD、CRP等可作为冠心病患者病情严重程度以及临床分型的预测性指标。

Objective To investigate the clinical features and risk factors of CHD patients of different clinical patterns. Methods From November 2010 to March 2011,118 CHD patients who needed PCI therapy admitted to General Hospital of PLA were selected. According to the retrospective investigation into clinical records of the research objects, the clinical characteristics, laboratory examination index and coronary arteriog- raphy results were compared among different clinical patterns in CHD patients. Results Among the 118 CHD patients,there were 46 cases of acute myocardial infarction（AMI） ,62 cases of unstable angina pectoris （UAP） ,and 10 cases of stable angina pectoris（SAP）. The proportion of smoker was higher in AMI group, the contractive pressure and pulse pressure on admission were lower than UAP and SAP group, but the rate of patients with grade 11I hypertension in AMI group was higher than SAP group. At the same time the value of WBC,CK,CK-MB, DD, CRP were higher in AMI group significantly. The difference of stenosis degree of coronary artery in the three groups had no statistical significance. Conclusion Smoking history,WBC,CK, CK-MB, DD,CRP can be used as predictive indexes for severity and clinical typing of CHD patients.