屎肠球菌DM891129菌株对大鼠高血脂症的调节作用

ADJUSTMENT OF ENTEREOCOCCUS FACIUM DM891129 STRAIN TO WISTAR RAT WITH HYPRTLIPEMIA

对屎肠球菌DM 891129 菌株进行调节血脂作用的功能实验。实验动物采用二级w istar 雄性大鼠,饲以高胆固醇脂饲料再同时饲以本活菌制剂。14 和28 天后,分别测定大鼠血清胆固醇(TC)、血清甘油三脂(TG)和血清高密度脂蛋白(HDL- C)。实验结果显示:实验组中高中低剂量组血清胆固醇浓度比对照组低(P< 0.05);血清TG 浓度、血清HDL- C 浓度、体重实验组与对照组相比组内和组间差异不明显。结果表明:与饲以高脂饲料的对照组大鼠相比,实验组的大鼠血清TC 浓度明显低于对照组(P< 0.05)。

As a probiotics the Entreococcus facium DM891129 was isolated from a healthy child This study aimed to investigate the effect on hyperlipemic wistar rats after administrated E Facium preparation after 14and 28 days The results showed that E. Facium preparation could decrease the serum choleesterol level in vitro and wistar rats. It can be confirmed that Enterococcus facium preparation has effect of ajjustting hyperlipemia of wistar rat.