肛周尖锐湿疣复发与HPV亚型的关系分析

Study the Relationship of the HPV Subtype and Perinal Condylomata Acuminatum Recurrent Rate

目的:分析肛周尖锐湿疣(CA)复发与人乳头瘤样病毒(HPV)不同亚型感染之间的关系。方法:从初诊时诊断肛周尖锐湿疣患者HPV检测单一亚型、混合亚型、未检出亚型三组中各随机选取患者20例,经多功能电离子治疗仪治疗后12周内连续观察记录各亚型患者复发情况,分析复发率与初诊时感染HPV亚型之间的关系。结果:HPV6,11/16,18混合型、单一亚型复发率与未检出亚型比较,差异有统计学意义(P<0.05)。结论:肛周尖锐湿疣复发率与初诊感染HPV亚型有关,未检出亚型及单一亚型感染复发率低于混合亚型感染,未检出亚型复发率最低。

Objective： To analyze the realationship of the HPV subtype and perinal condylomata acuminatum recurrent rate and conclude which subtype the patients belong to shoud be visited strictly in order to reduce recurrence of perinal condylomata acuminatum. Methods： 20 patients were randomly selected from patients who were dignosed perinal condylomata acuminatum in the first time and whoes subtype was single subtype, compound subtype and the negtive respectively. They were all treated by multifunctional electronic therapeutic instrument only. In the next 12 weeks, every patient was visited one time a week in order to know whether the disease recurred. Compared the diffrence of perinal condylomata acuminatum recurred rates among three groups. Results： Recurrate of compound subtype was evidently different from the others （ P 〈 0.05 ）, and the negtive group was evidently different from the others too （ P 〈 0.05 ）. Conclusion： Recurred rates of perinal condylomata acuminatum is closely re- lated to the HPV subtype, the compound subtype was the highest, the negtive group was the lowest.