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冻干人纤维蛋白原加热处理灭活病毒的研究 被引量：1

Probing virus inactivation of lyophilized human fibrinogen by heating
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摘要 本试验比较了多种加热病毒灭活方法 ,包括巴斯德消毒法、干热灭活法等。发现 6 0℃ 144小时干热灭活病毒可能适合于纤维蛋白原的生产。 Tested and compared were many heat treated virus inactivation methods including pasterurization,dry heating virus inactivation et al.60℃ 144h dry heating was found to be suitable for preparation of fibrinogen probably.
作者 李征 熊祥政 王焰 陈品全
机构地区 成都生物制品研究所
出处 《微生物学免疫学进展》 2000年第1期41-43,共3页 Progress In Microbiology and Immunology
关键词 纤维蛋白原 病毒灭活 热处理 Fibrinogen Virus inactivation Heat treated.
分类号 R457 [医药卫生—治疗学]
  • 相关文献

参考文献9

  • 1Murphy P,Nowak T,Lemon SM,et al.Inactivation of hepatitis A virus by heat treatment in aqueous solution[].Journal of Medical Virology.1993
  • 2Barrett PN,Meyer H,Wachtel I,et al.Inactivation of hepatitis A virus in plasma products by vapor heating[].Transfusion.1997
  • 3Peerlinck K,Vermylen J.Acute hepatitis A in patients with haemophilia A[].The Lancet.1993
  • 4Hart HF,Hart WG,Crossley J,et al.Effect of terminal(dry) heat treatment on nonenveloped viruses in coagulation factor concentrate[].Vox Sanguinis.1994
  • 5Manucci PM.Outbreak of Hepatitis A among Italian patients with haemophia[].The Lancet.1992
  • 6Dichtelm¨uller H,Rudnick D,Breuer B,et al.Improvement of virus safety of a S/D-treated factor Ⅷ concentrate by additional dry heat treatment at 100℃[].Biologicals.1996
  • 7Knevelman A,deWit HJC,Potstra P,et al.Development and smallscale production of a severely heated factor Ⅷ concentrate[].Vox Sanguinis.1994
  • 8Gerritzen A,Schneweis KE,Brackmann HH,et al.Acute hepatitis A in haemophiliacs[].The Lancet.1992
  • 9Temperley IJ,Cotter KP,Walsh TJ,et al.Clotting factor and hepatitis A[].The Lancet.1992

同被引文献4

  • 1Manucci PM.Outbw.ak of heaptifis A among Italian patients with haemophia[J.Lancet 1992,339:819.
  • 2Peeriinck K,Vermylen J.Acute hepatitis A in patient with haemophia A[J].Lancet 1993,341:179.
  • 3Knevelman A,deWit HJC,Potstra P,et al.Development and smallscale production of a severely heated factor Ⅷ concentra[J].Vox Sang 1994,66:89-95.
  • 4Dichtelmuller H,Rudnick D,Breuer B,et al.Improvement of vires safety of a S/D-treated factor Ⅷ concentrate by additional dry beat treatment at 100℃[J].Biologicals 1996,24:125-130.

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微生物学免疫学进展
2000年 第1期

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