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结核分枝杆菌分泌蛋白研究进展 被引量：3

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摘要 结核分枝杆菌 (MTB)的分泌蛋白是目前发现对MTB感染保护性最好的一组蛋白 ,对结核病的预防和诊断具有重要意义。本文从其组成、生物学功能、免疫性及其在疫苗研制和MTB诊断中的潜在价值作一概述。
作者 白光春 马文煜
机构地区 第四军医大学微生物学教研室
出处 《微生物学免疫学进展》 2000年第1期81-83,共3页 Progress In Microbiology and Immunology
关键词 结核分枝杆菌 分泌蛋白 胞外蛋白
分类号 R378 [医药卫生—病原生物学]
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参考文献10

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同被引文献40

  • 1柏银兰,薛莹,李元,徐志凯,师长宏,张海.结核分枝杆菌分泌蛋白MPT64的免疫学特性[J].第四军医大学学报,2004,25(13):1182-1184. 被引量：6
  • 2John B K, Charles O T. Tuberculosis [J]. Zoonosis Update, 2004, 224: 685-691.
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  • 5Tollefsen S, Vordermeier M, Ulsen I, et al. DNA injection in combination with electroporation a novel method for vaccination of farmed ruminants [J]. Scandinavian Journal of Immunology, 2003, 57: 229-238.
  • 6Launois P, R DeLeys, M N Niang, et al. T-cell-epitope mapping of the major secreted mycobacterial antigen Ag85A in tuberculosis and leprosy [J]. Immun, 1994, 62: 3679-3687.
  • 7Roche P W, C G Feng, W J Britton. Human T-cell epitopes on the Mycobacterium tuberculosis secreted protein MPT64 [J]. Scand J Immunol, 1996, 43: 662-670.
  • 8Ida Rosenkrands, Karin Weldingh. Mapping and identification of Mycobacterium tuberculosis proteins by two-dimensional gelelectrophoresis, microsequencing and immunodetection [J]. Electrophoresis, 2000, 21: 935-948.
  • 9Ida Rosenkrands, Angus King. Towards the proteome of Mycobacterium tuberculosis [J]. Electrophoresis, 2000, 21 : 3740-3756.
  • 10Chambers M A, Vordermeier H, Whelan A, et al. Vaccination of mice and cattle with plasmid DNA encoding the Mycobacterium bovis antigen MPB83 [J]. Clin Infect Dis, 2000, 30: 283-287.

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微生物学免疫学进展
2000年 第1期

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